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Trial Summary Table

Trial Name Phase Start Date Sponsors Countries Population Candidate(s) Status Expected Completion Date
Implementation of the Pre-Exposure Prophylaxis (PrEP) to HIV in Brazilian transgender women (PrEParadas) Demo Project Thursday, July 12, 2018 Brazilian Ministry of Health Brazil Ongoing July 2020
Impower 022 III Wednesday, February 24, 2021 Merck Sharp & Dohme Corp. United States of America, South Africa Women Islatravir (MK-8591), TDF/FTC (Truvada) Stopped Early July 2024
Impower 024 III Monday, March 15, 2021 Merck Sharp & Dohme Corp. Men, MSM, Transgender women Islatravir (MK-8591) Stopped Early September 2024
IPERGAY III Wednesday, February 22, 2012 French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS), the Canadian Trial network, Bill and Melinda Gates Foundation, Fondation Pierre Bergé, Gilead Sciences Canada, France MSM TDF/FTC (Truvada) Completed June 2016
IPM 056 / CCN019B I/II Wednesday, June 1, 2022 IPM, NICHD, NIH United States of America Women Dapivirine-Levonorgestrel ring Ongoing September 2023
iPrEx III Saturday, June 30, 2007 Bill & Melinda Gates Foundation, NIAID United States of America, Brazil, Ecuador, Peru, South Africa, Thailand MSM TDF/FTC (Truvada) Completed February 2014
iPrEx OLE Open Label Saturday, July 9, 2011 DAIDS/NIH, through a grant to the Gladstone Institutes Peru, United States of America, Brazil, Thailand, South Africa, Ecuador MSM TDF/FTC (Truvada) Completed April 2014
Ireland Demonstration Project Demo Project Sunday, December 18, 2016 Ireland Planned December 2017
LAC PATH PrEP Demo Project Demo Project California HIV/AIDS Research Program of the University of California; LA County HIV & STD Program; Los Angeles Gay and Lesbian Center; OASIS Clinic; AIDS Project LA; UCLA United States of America MSM TDF/FTC (Truvada) Completed May 2017
LVCT Health and SWOP Kenya (IPCP - Kenya) Demo Project Saturday, August 1, 2015 Bill & Melinda Gates Foundation Kenya Women, Men, MSM Ongoing April 2017

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