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Multipurpose Prevention Technologies

HIV prevention and women’s reproductive health go hand in hand.

HIV prevention doesn’t happen in isolation. Even when people are at high risk for HIV, avoiding infection is but one factor in a complex set of decisions about their health and well-being. For women worldwide, those decisions include childbearing and reproductive and sexual health.

Multi-purpose prevention technologies are now in development to simultaneously prevent unintended pregnancy and protect against HIV and other sexually transmitted infections. By addressing multiple health concerns in convenient, easy-to-use formulations, these technologies might also help ensure high levels of product adherence. Multiple versions are entering early clinical trials now. Many important questions about efficacy, acceptability and adherence need to be addressed as this research proceeds.

The Dual Prevention Pill (DPP) is currently being developed for daily use to prevent both HIV and pregnancy. Among several MPTs in the pipeline, The DPP, combining TDF/FTC-based oral PrEP with oral contraceptives (OC), is furthest along in development, learn more here.

What We're Reading

Vaginal Ring Acceptability: A Systematic Review and Meta-analysis of Vaginal Ring Experiences from around the World

Women who used vaginal rings reported they were acceptable across indications geographic regions and indications. Policy makers should consider the ring as an important option for pregnancy and HIV prevention drug development.

October 10, 2021
Microbicides, Multipurpose Prevention Technologies
Contraception

Multipurpose Prevention Technologies: Oral, Parenteral, and Vaginal Dosage Forms for Prevention of HIV/STIs and Unplanned Pregnancy

This review gives a comprehensive overview of the latest oral, parenteral, and vaginally delivered MPTs in development as well as drug delivery formulations with the potential to advance as an MPT, and implementation studies regarding MPT user acceptability and adherence. Despite the challenges in the MPT landscape, these technologies demonstrate the potential to bridge gaps in preventative sexual and reproductive health care.

July 26, 2021
Multipurpose Prevention Technologies
Polymers
Featured Resources

Multipurpose Prevention Technologies (MPTs): Technology Landscape and Potential for Low- and Middle-Income Countries

This landscape report provides an overview of the current novel technologies in development and assesses their relevance and potential in low- and middle-income countries. While the pipeline is rich, the report calls out the need to involve key populations early in the design, introduction and scale-up of new products and proactively address potential market barriers.

December 2021
Unitaid
Initiative for Multipurpose Prevention Technologies
Children’s Investment Fund Foundation
Multipurpose Prevention Technologies
Report/Issue Brief

Advocates' Guide to Multipurpose Prevention Technologies

A resource to support advocacy for multipurpose prevention technologies (MPTs). The Guide calls out four areas ripe for advocate involvement. It also provides a snapshot on the status of MPT research and development and data on investments—critical information that can support evidence-based advocacy.

May 2021
AVAC
Microbicides, Multipurpose Prevention Technologies, PrEP
Fact Sheet
Report/Issue Brief

AVAC Report 2019: Now What?

At the threshold of 2020, it’s clear that global goals for HIV prevention will miss the mark by a long shot. Though important progress has been made, the crisis UNAIDS called out in 2016 persists today with new infections around 1.7 million annually, a far cry from the 2020 target of fewer than 500,000. So, we asked ourselves, Now What?, and answered with cross-cutting analysis and an advocacy agenda to match.

November 2019
AVAC
HIV Vaccine, Combination Prevention, Male and Female Condoms, Cure, Hormonal Contraceptives and HIV, Microbicides, Multipurpose Prevention Technologies, PrEP, Treatment, Voluntary Medical Male Circumcision
AVAC Report

A Ten-Year Retrospective Report on the IMPT

A 10-year retrospective on advances in the field of multi purpose technologies by the Intiative for Multipurpose Prevention Technologies (IMPT), a project of CAMI Health. The report is also available online on the IMPT website.

November 2019
IMPT
Multipurpose Prevention Technologies
Report/Issue Brief

MPT Target Population Identification Mapping Tool

This interactive map produced by the IMPT for Reproductive Health illustrates the overlap in HIV prevalence in women and the total addressable market for contraception (women currently using a modern method as well as those who plan to use contraception in the future). This suggests hot spots where an MPT that combines HIV prevention and contraception might have the greatest impact.

October 2019
IMPT
Multipurpose Prevention Technologies
Website
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