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Trial Summary Table

Trial Name Phase Start Date Sponsors Countries Population Candidate(s) Status Expected Completion Date
PrEPVacc / PV1 IIb Wednesday, January 1, 2020 Sponsor: Imperial College London. Coordinating partners: P Kaleebu, E Ruzagira (MRC/UVRI & LSHTM, Uganda); J Weber/J Fox/C Kingsley (Imperial College, UK); S McCormack (UCL, UK); K Chinyenze (IAVI-Kenya); G Pantaleo/S Ding (CHUV/EVF, Switzerland) Uganda, South Africa, United Republic of Tanzania, Mozambique Men, Women DNA , MVA, Protein Ongoing December 2024
PrEPX Demo Project Tuesday, July 26, 2016 Victorian Government, Alfred Health and the Victorian AIDS Council Australia Women, Men, MSM Ongoing March 2018
Project PrEPare (Adolescents 18-22) Demo Project Friday, November 30, 2012 Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) United States of America MSM TDF/FTC (Truvada) Ongoing November 2015
PROUD (pilot trial) IV Wednesday, October 31, 2012 Medical Research Council United Kingdom Men, MSM TDF/FTC (Truvada) Completed October 2016
PSI Private Sector PrEP Program Open Label Friday, November 11, 2016 UNITAID; PSI South Africa Women Planned
PURPOSE 2 III Monday, June 14, 2021 Gilead Sciences United States of America Men, MSM, Transgender men, Transgender women Lenacapavir , F/TDF Ongoing April 2027
PURPOSE 3/ HPTN 102 Open Label Women Lenacapavir , TDF/FTC (Truvada) Planned
Purpose 4/ HPTN 103 Open Label Injecting drug users Lenacapavir Planned
Queensland PrEP Demonstration Project (QPrEP) Demo Project Tuesday, September 29, 2015 Queensland Health/HIV Foundation Queensland Australia MSM Ongoing November 2016
Right to Care (DREAMS) Demo Project PEPFAR, BMGF, Nike Foundation Planned

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