With long-acting injectable PrEP coming to market, how can we mitigate barriers and adopt the intervention widely in high-risk settings? On Wednesday, November 10, Evidence to Action, the webinar series hosted by the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF), heard from experts at Johns Hopkins University, United States Agency for International Development (USAID), AVAC, Asia Pacific Coalition on Male Sexual Health (APCOM), and EGPAF on what’s new in PrEP, the present and future of long-acting injectables, what actions to take for optimal implementation and how we can better enable access in key populations.