Africa Health R&D Week 2022 is designed to recognize achievements and step up advocacy for sustainable financing of health R&D through domestic resource mobilization (DRM) in Africa. The week contains a series of informative, networking, and motivational events for advocates, media, policymakers, program implementors, researchers, and funders to bring clarity to key issues and trends of DRM for health R&D on the continent. The content and programming of Africa Health R&D Week is informed by the various coalitions advocating for DRM for health.