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HPTN 074

Status
Completed
Phase
Open Label
III
Principal Investigator(s)
William Miller
Objective

 

The purpose of this study is to determine the feasibility of a future trial that will assess whether an integrated intervention combining psychosocial counseling and supported referrals for antiretroviral therapy (ART) at any CD4 cell count and substance use treatment for HIV-infected people who inject drugs (PWID) will reduce HIV transmission to HIV-uninfected injection partners, as compared to routine care dictated by national guidelines for HIV-infected PWID.

Last updated June 10, 2022

Prevention Option(s)
PrEP
Treatment
Study Design
Randomized
Open label
Arms and Assigned Interventions
Description
Experimental: Integrated Intervention Standard of care plus an integrated system of psychosocial counseling and systems navigation for HIV treatment and Substance Use treatment
ARMs
Experimental
Trial Sponsors
HPTN, NIDA, NIAID
February 2015
June 2018
Date of Enrollment Completion
June 16, 2017
Enrollment
1 281
18
Years
45
Years
Population
HIV positive
Injecting drug users
Sites

CIPTO

Jakarta
Indonesia

Ukrainian Institute on Public Health Policy

Kiev
Ukraine

Pho Yen Health Center

Pho Yen, Thai Nguyen
Thailand