CLIP Ring

Phase

Pre-clinical

Principal Investigator(s)

BENHABBOUR, SOUMYA RAHIMA

Objective

Islatravir Etonogestrel/Ethinyl Estradiol (EFdA) 3D Printed IVR

Our paramount innovation is use of digital light synthesis – a novel 3D printing process known as continuous liquid interface production (CLIP™) – for rapid, scalable, and cost-effective manufacturing of geometrically and mechanically tunable, rationally designed intravaginal rings as platforms for multi-drug delivery.

Abstract presented at CROI 2022 See poster here

Last updated September 20, 2022

Prevention Option(s)

Microbicides

Multipurpose Prevention Technologies

Arms and Assigned Interventions

Description

Active Ingredient: Etonogestrel Ethinyl Estradiol Islatravir (EFdA)

Mode of Delivery

Ring

Products

Islatravir (MK-8591)

Official Code

Islatravir (EFdA) + Etonogestrel/Ethinyl Estradiol 3D Printed IVR

Related Publications

1R01AI150358-01

Multipurpose Prevention Technologies: Oral, Parenteral, and Vaginal Dosage Forms for Prevention of HIV/STIs and Unplanned Pregnancy

Next-generation Islatravir/Etonogestrel/Ethinyl Estradiol MPT Intravaginal Ring

Trial Sponsors

CDC, NIAID

Product Developers

UNIV OF NORTH CAROLINA CHAPEL HILL

December 2019

November 2024

Population

Men

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CLIP Ring