Email Updates

You are here

Home

CDC 4370/ Bangkok TFV Study

Status
Completed
Phase
III
II
Principal Investigator(s)
Kachit Choopanya, MD
Objective


To assess the safety and efficacy of daily tenofovir to prevent parenteral HIV infection among injection drug users (IDU) in Thailand. IDU was defined as individuals who reported substance use in the past year from the time they were screened.

Key results: There was a 49% reduction in HIV infection rate among IDU in Thailand with Daily oral TDF.

Last update August 10, 2022

Prevention Option(s)
PrEP
Study Design
Controlled
Randomized
Double-blind
Arms and Assigned Interventions
Description
Daily dosing
Mode of Delivery
Tablet
Products
TDF
ARMs
Experimental
Description
Daily dosing
Mode of Delivery
Tablet
ARMs
Placebo Comparator
Results
[June 2013] Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (Bangkok Tenofovir Study)
Official Code
NCT00119106
Related Publications
Enrollment characteristics and risk behaviors of injection drug users participating in the Bangkok Tenofovir Study, Thailand.
Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial
Factors associated with the uptake of and adherence to HIV pre-exposure prophylaxis in people who have injected drugs: an observational, open-label extension of the Bangkok Tenofovir Study
The impact of adherence to preexposure prophylaxis on the risk of HIV infection among people who inject drugs
Risk behaviors and risk factors for HIV infection among participants in the Bangkok tenofovir study, an HIV pre-exposure prophylaxis trial among people who inject drugs
Trial Sponsors
Bangkok Metropolitan Administration Medical College and Vajira Hospital, Thailand Ministry of Health, US CDC
Product Developers
Gilead Sciences, Inc.
June 2005
October 2014
Date of Enrollment Completion
July 1, 2013
Enrollment
2 413
20
Years
60
Years
Population
Injecting drug users
Sites

Site(s) - Thailand

Thailand