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The Handbook provides comprehensive introductory material on the key scientific, policy, social, ethical and economic facets of AIDS vaccine research. While the science has changed greatly over the decade since this second edition of the Handbook was published in 2005, the themes and content in many of the essays still hold true. Edited by Patricia Kahn, the handbook contains articles by community educators and advocates, trial staff and volunteers, scientists and researchers, and policy makers and journalists.