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In this report, AVAC offers its first contribution to the scenario planning critical to the success of the field. The next several years bring a variety of scenarios which cannot be encountered unprepared. Instead, the AIDS vaccine field, and the field of prevention research in general, must engage in rigorous debate, dialogue and scenario planning which anticipates the issues that the next few years will bring, and ensures that the wide range of stakeholders are informed and empowered to make decisions to compete against the virus. In this report, four thought-provoking chapters are presented, each of which begins with a future scenario that considers how the world might look in five or six or ten years' time.