To arrive at a point in 2030 where the rate of new infections is negligible is an ambitious aim, but not a foolish one. The tools to achieve it exist, and those at the 20th International AIDS Conference, held this week in Melbourne, are sharpening them. Sadly, though, six delegates on their way to the conference were killed when flight MH17 was shot down over eastern Ukraine on July 17th. One of those delegates was Joep Lange, a former president of the International AIDS Society (see obituary). But their work goes on.