HVTN Trial Results and Implications for Future Research

The US National Institute of Allergy and Infectious Diseases (NIAID) and HIV Vaccine Trials Network (HVTN) accounced that the HVTN 505 AIDS vaccine clinical trial would cease immunizations early after the independent Data and Safety Monitoring Board (DSMB) determined during a scheduled interim review that the vaccine regimen being tested is not effective.

Trial investigators Scott Hammer and Madgalena Sobieszczyk were joined by statisticians Holly Janes and Peter Gilbert to discuss these results and take questions.