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As a global leader in biomedical and behavioral research, NIH is committed to supporting collaborative international research that harnesses the rich diversity of the biomedical workforce to advance timely solutions to global health challenges. Therefore, NIH has a responsibility to identify and address, to the extent possible given its mission, the challenges and barriers to equitable research, which for the purposes of this RFI is defined as research collaboration that is inclusive, elevates underrepresented voices and groups, and demonstrates fairness of opportunity and fair process. This Notice is a Request for Information (RFI) on approaches NIH can take to promote greater equity in global health research, particularly research that engages scientists in low and middle-income countries (LMICs).